Accutane (isotretinoin) is intended for the treatment of patients with severe recalcitrant nodular acne that did not respond to antibiotics. Call your health care provider immediately if you have unprotected sex or you missed your period, as there is a risk you may get pregnant and your baby may be affected. Accutane needs to be taken regularly and any strange or bothersome side effects need to be reported. Make sure you tell your health care provider if you get frequent urination, fever, unusual thirst, difficulty hearing, yellowing of the skin or eyes, vision problems, rectal bleeding, rash, diarrhea, painful dryness of the eyes, pounding heartbeat, dark colored urine, joint or muscle pain, muscle weakness, or worsening heartburn, as any of the serious side effects mentioned can mean your treatment is not going quite as planned. You can continue taking Accutane and talk to your doctor if you get the following symptoms: joint pain, cracking or peeling skin, changes in your fingernails, dryness of the lips, mouth, nose, or skin, dizziness, nervousness, back pain, and drowsiness. In most cases Accutane does not cause side effects in people taking it.